NAPROCAP

Dosage

1,250 mg/m2 bid for 2 wk followed by 1-wk rest period given as 3-wk cycles. Combination w/ docetaxel: 1,250 mg/m2 bid for 2 wk followed by 1-wk rest period + docetaxel 75 mg/m2 1 hr IV infusion every 3 wk.

Indication

Single agent for adjuvant treatment in patients w/ Dukes C colon cancer who have undergone complete resection of the primary tumor when treatment w/ fluoropyrimidine therapy alone is preferred. Treatment of patients w/ metastatic breast cancer after failure of prior anthracycline-containing chemotherapy.